Regardless of if I am talking about the NFL, CFL, NCAA, Arena League or upcoming XFL, the point spread is the most popular wagering option for bettors who love to test football betting skills. The point spread is an indication of which team is the favorite and underdog heading into their matchup. In college football odds, a seven-point spread means that the favorite in the game will have seven points taken from their total if you back them. Conversely, backing the underdog will see a bettor’s selection get seven points added to it. Throw fantasy-style props wagers and live NCAA betting into the mix and the importance of understanding how college football odds operate is at an all-time high. Check out the lines and bookmark the page for more updates and football lines enhancements in the coming weeks and months.

Top Conferences

If my memory serves correct, you’d additional info have to go back to the infamous blocked punt and touchdown return by the Spartans to the last time both teams were relevant. Both teams are currently 7-0 on the season, but it’s the Wolverines who are ahead in the rankings as they sit at No. 6. Either way, the winner of this game will be undefeated but must still go head-to-head with Ohio State, and we know that’s no walk in the park. As for this contest, I believe the Wolverines are the more complete team and I believe their defense will make one more play and limit what the Spartans can do offensively.

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There are around 130 teams and that means a huge amount of matches are priced up by the bookies. The bookies make the 2021 NCAA Division I FBS football season a battle of four teams who are all trading at single figure betting odds. LSU won the 2019 National Championship but regressed to 5-5 in 2020. While they started slow, LSU improved steadily throughout the season and knocked off Florida towards the end of the season. This year they return nine starters on both sides of the ball.

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Stanford is 115th in college football, gaining 312.4 yards per game, while Cal ranks 60th in yards conceded (363.0). Bettors who wager on the point spread or over/under market usually look for a close to even return on their investment. However, moneyline bettors are either looking for a higher probability chance of winning or a more significant return of their money by backing the underdog. Regular underdog bettors are sometimes known as "sharps", a term you may have heard within the industry. This is because they usually fade the public opinion and side with the lower probability outcome, resulting in a larger return on their investment.

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Betting on the 2021 NCAA College Football Championship winner? Take advantage of these brilliant new customer betting offers. Meanwhile, the Pirates struggled to contain the Appalachian State rushing attack in Week 1, as the duo of Nate Noel and Camerun Peoples combined for 226 yards on 29 total carries. East Carolina missed eight tackles on 34 run-defense snaps, allowing 0.190 expected points added per rush, one of the worst marks of the weekend. Click here for PFF Greenline’s cover probabilities for side, total and moneyline. Iowa +5 is now +4.5, Ohio State -10 is now -14.5, and Texas -3.5 is now -6.5.

It can also tell you a potential payout based off of what you want to bet. Here are the most common odds you’ll see posted throughout the college football season. See college football picks for every single game, including this one, from SportsLine's advanced computer model.

An avid follower of the sports betting industry since a young age, Anthony has written betting columns and predictions for various sites including,, and now Covers. Timmy McClain leads the team with 1,000 passing yards (142.9 yards per game) and has a 56.9% completion percentage this year (74-of-130) while throwing two touchdowns with two interceptions. He also has 219 rushing yards on 74 carries with one touchdown, averaging 31.3 yards per game.

From the latest Super Bowl odds to the exhilarating MVP race that seems to take shape every year, PFN has the pro football gambler covered 365 days a year. Other programs high on the list for betting odds includes Baylor, Duke, Florida State, Louisville and Wisconsin. Mark Few has a star-studded duo he can rely on in Filip Petrusev and Corey Kispert. The Bulldogs also hold claim to the No. 9 recruiting class in the country, per 247Sports.